Potato juice encapsulation into liposomes
Anna Bryła
kbimz@up.poznan.plKatedra Biotechnologii i Mikrobiologii Żywności, Uniwersytet Przyrodniczy w Poznaniu (Poland)
Wojciech Juzwa
Katedra Biotechnologii i Mikrobiologii Żywności, Uniwersytet Przyrodniczy w Poznaniu (Poland)
Grażyna Lewandowicz
Katedra Biotechnologii i Mikrobiologii Żywności, Uniwersytet Przyrodniczy w Poznaniu (Poland)
Abstract
The potato juice is a material of various biological activities. It reveals anti-inflammatory effect within gastrointestinal tract, as well as antiproliferative activity against stomach and intestine cancer cells. Moreover, it stimulates the growth of probiotic Lactobacillus and Bifidobacterium, inhibiting the development of pathogens — Clostridium perfringens and E. coli at the same time. However, due to the high susceptibility of potato juice bioactive substances to degradation by light, oxygen and possible interaction in the food product, the use of potato juice for food products fortification may be limited. Encapsulation into liposomes may be the solution. The aim of this study was to evaluate the usefulness of lecithin of different biological origins for the encapsulation of potato juice into liposomes by a thin film hydration method. Prior to encapsulation process, potato juice was subjected to cryoconcentration and then to a proteolysis performed in a membrane reactor equipped with an ultrafiltration separation unit. The hydrolysate was diluted in phosphate buffered saline and encapsulated into liposomes. Liposomes were prepared by thin lipid film hydration technique. Size distribution of the obtained particles was determined by dynamic light scattering method as well as was their stability by the ζ potential measurement. At the same time, the nanocapsules morphology was studied by flow cytometry. Additionally, the encapsulation process efficiency was evaluated. It was found that, both sunflower and soya lecithin may be used for potato juice hydrolysate encapsulation into liposomes. Egg yolk lecithin, due to the unsatisfactory encapsulation efficiency cannot be recommended for this purpose. The highest encapsulation yield was observed for sunflower lecithin, but the obtained liposomes were characterized by relatively low stability. Soy lecithin however, provided stable liposomes with a satisfactory efficiency, and without a necessity of a strong dilution of the hydrolysate in a phosphate buffer saline. It was shown that the obtained population of liposomes was homogeneous both in terms of size and structure of the nanocapsules.
Supporting Agencies
Keywords:
hydrolysate, liposome, nanocapsule, potato juceReferences
Atkins W. A. Chemia fizyczna. Wydawnictwo Naukowe PWN, Warszawa 2007.
Google Scholar
Bangham A. D., Standish M. M., Watkins J. C. 1965. Diffusion of univalent ions across the lamellae of swollen phospholipids. J Mol Biol. 13 (1): 238 — 252.
Google Scholar
Charcosset C., El-Harati A., Fessi H. 2005. Preparation of solid lipid nanoparticles using a membrane contactor, J of Controlled Release, 108: 112 — 120.
Google Scholar
Chen Y., Lu Y., Chen J., Lai J., Sun J., Hu F., Wu W. 2009. Enhanced bioavailability of the poorly water-soluble drug fenofibrate by using liposomes containing a bile salt, Int. J. Pharm. 376: 153 — 160.
Google Scholar
Delgado A.V., González-Caballero F., Hunter R.J., Koopal L.K., Lyklema J. 2005. Measurement and interpretation of electrokinetic phenomena (IUPAC Technical Report). Pure & Applied Chemistry 77 (10): 1753 — 1805.
Google Scholar
Hope M. J., Bally M. B., Webb G., Cullis P. R. 1985. Production of large unilamellar vesicles by a rapid extrusion procedure. characterization of size, distribution, trapped volume and ability to maintain a membrane potential. Biochim Biophys Acta 812: 55 — 65.
Google Scholar
Jaafar-Maalej C., Charcosset C., Fessi H. 2011. A new method for liposome preparation using a membrane
Google Scholar
Contactor. J. Liposome Res. 21 (3): 213 — 220.
Google Scholar
Keller B.C. 2001. Liposomes in nutrition. Trends Food Sci. Tech. 12: 25 — 31.
Google Scholar
Khosrevi-Darani K., Pardekhty A., Homerpishek H., Rao M., Mozafari M. R. 2007. The role of high-resolution imaging in the evaluation of nanosystems for bioactive encapsulation and targeted nannotherapy. Micron. 38: 804 — 818.
Google Scholar
Kowalczewski P., Celka K., Białas W., Lewandowicz G. 2012a. Antioxidant activity of potato juice. Acta Sci. Pol. Technol. Aliment. 11 (2): 175 — 181.
Google Scholar
Kowalczewski P., Lewandowicz G., Makowska A., Olejnik A., Obuchowski W. 2012b. Charakterystyka ekstrudowanych przekąsek zbożowych zawierających sok z ziemniaka. Biul. IHAR 266: 319 — 329.
Google Scholar
Kozubek A. 2004. Wstęp do technologii liposomowej. Wrocław. Dostępne na: http://www.ibmb.uni. wroc.pl/studia/liposomes.pdf.
Google Scholar
Lee, H. S. 2005. Clinical effects of intake of Juice valley and Gogu valley towards fecal microflora of healthy human volunteers. Food Sci. Biotechnol. 14: 540 — 542.
Google Scholar
Lewandowicz G., Leja K., Lubiewski Z., Białas W. Dembczyński R. 2010. Wpływ obróbki wstępnej soku ziemniaczanego na przebieg hydrolizy enzymatycznej frakcji białkowej w reaktorze membranowym. W: Membrany i Procesy Membranowe w Ochronie Środowiska. Monografie Komitetu Inżynierii Środowiska vol. 65: 363 — 371.
Google Scholar
Lewandowicz G., Kowalczewski P., Białas W., Olejnik A., Rychlik J. 2012. Rozdział frakcji soku ziemniaczanego różniących się masą cząsteczkową i charakterystyka ich aktywności biologicznej. Biul. IHAR 266: 331 — 344.
Google Scholar
Lewandowicz G., Kowalczewski P., Olejnik A., Jodynis-Liebert J., Kujawska M., Lesiecki M. 2014. Sposób otrzymywania preparatu z soku ziemniaka oraz jego zastosowanie. Zgłoszenie Patentowe PL nr P.406918 z dnia 24.01.2014.
Google Scholar
Lubiewski Z., Śmigielska H., Lewandowicz G., Balcerek W. 2006. Charakterystyka odcieku po koagulacji białka pozyskiwanego w toku kampanii krochmalniczej. Zesz. Probl. Post. Nauk Rol. z. 511: 617 — 626.
Google Scholar
Meure L. A., Foster N. R., Dehghani F. 2008. Conventional and dense gas techniques for the production of liposomes: a review. AAPS Pharm Sci. Tech. 9 (3): 789 — 809.
Google Scholar
Mozafari M. R., Khosravi-Darani K., Borazan G. G., Cui J., Pardakhty A., Yurdugul S. 2008. Encapsulation of food ingredients using nanoliposome technology. International Journal of Food Properties, 11: 833 — 844.
Google Scholar
Olejnik A., Białas W., Tomczyk J., Lewandowicz G. 2011. Cytotoksyczność i genotoksyczność soku z ziemniaka. Zeszyty Naukowe Uniwersytetu Ekonomicznego w Poznaniu 205: 118 — 125.
Google Scholar
Papahadjopoulos D., Miller N. 1967. Structural characteristics of hydrates liquid crystals. BBA. 75067: 624 — 638.
Google Scholar
Pouvreau L., Gruppen H., Piersma S.R., van den Broek A. M., van Koningsveld G. A., Voragen A. G. J. 2001. Relative abundance and inhibitory distribution of protease inhibitors in potato juice from cv. Elkana. J. Agr. Food Chem. 49: 2864 — 2874.
Google Scholar
Ruseler-van Embden J. G. H., van Lieshout L. M. C., Laman J.D. 2004. Methods and means for preventing or treating inflammation or puritis, Patent USA 6:723,354.
Google Scholar
Ruysschaert T., Marque A., Duteyrat J. L., Lesieur S., Winterhalter M., Fournier D. 2005. Liposomes retention in size exclusion chromatography. BMC Biotechnology 5 (11).
Google Scholar
Sato K., Obinata T., Sugawara., Urabe I., Yomo T. 2006. Quantification of structural properties of cel-sized individual liposomes by flow cytometry. J Biosci Bioeng, 102 ( 3): 171 — 178.
Google Scholar
Shew. R. L., Deamer D. W. 1985. A novel method for encapsulation of macromolecules in liposomes. Biochem. Biophis. Acta 816: 1 — 8.
Google Scholar
Wagner A, Vorauer-Uhl K., Katinger H. 2002. Liposomes produced in a pilot scale: production, purification and efficiency aspects, Eur. J. Pharm. Biopharm. 54: 213 — 219.
Google Scholar
Wagner A., Platzgummer M., Kreismayr G., Quendler H., Stiegler G., Ferko B., Vecera G., Vorauer-Uhl K., Katinger H. 2006. GMP Production of liposomes-a new industrial approach. J Liposome Res. 16: 311 — 319.
Google Scholar
Vorauer-Uhl K., Wagner A., Katinger H. 2002. Long term stability of rh-Cu/Zn-superoxide dismutase (SOD)-liposomes prepared by the cross-flow injection technique following International Conference on Harmonisation (ICH)-guidelines. Eur. J. Pharm. Biopharm. 54: 83 — 87.
Google Scholar
Authors
Anna Bryłakbimz@up.poznan.pl
Katedra Biotechnologii i Mikrobiologii Żywności, Uniwersytet Przyrodniczy w Poznaniu Poland
Authors
Wojciech JuzwaKatedra Biotechnologii i Mikrobiologii Żywności, Uniwersytet Przyrodniczy w Poznaniu Poland
Authors
Grażyna LewandowiczKatedra Biotechnologii i Mikrobiologii Żywności, Uniwersytet Przyrodniczy w Poznaniu Poland
Statistics
Abstract views: 87PDF downloads: 56
License
Copyright (c) 2014 Anna Bryła, Wojciech Juzwa, Grażyna Lewandowicz
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Upon submitting the article, the Authors grant the Publisher a non-exclusive and free license to use the article for an indefinite period of time throughout the world in the following fields of use:
- Production and reproduction of copies of the article using a specific technique, including printing and digital technology.
- Placing on the market, lending or renting the original or copies of the article.
- Public performance, exhibition, display, reproduction, broadcasting and re-broadcasting, as well as making the article publicly available in such a way that everyone can access it at a place and time of their choice.
- Including the article in a collective work.
- Uploading an article in electronic form to electronic platforms or otherwise introducing an article in electronic form to the Internet or other network.
- Dissemination of the article in electronic form on the Internet or other network, in collective work as well as independently.
- Making the article available in an electronic version in such a way that everyone can access it at a place and time of their choice, in particular via the Internet.
Authors by sending a request for publication:
- They consent to the publication of the article in the journal,
- They agree to give the publication a DOI (Digital Object Identifier),
- They undertake to comply with the publishing house's code of ethics in accordance with the guidelines of the Committee on Publication Ethics (COPE), (http://ihar.edu.pl/biblioteka_i_wydawnictwa.php),
- They consent to the articles being made available in electronic form under the CC BY-SA 4.0 license, in open access,
- They agree to send article metadata to commercial and non-commercial journal indexing databases.
Most read articles by the same author(s)
- Joanna Le Thanh-Blicharz, Jacek Anioła, Aleksander Walkowski, Grażyna Lewandowicz, Digestibility of diets containing RS modified starches assessment in rats , Bulletin of Plant Breeding and Acclimatization Institute: No. 266 (2012): Regular issue
- Przemysław Kowalczewski, Grażyna Lewandowicz, Agnieszka Makowska, Agata Olejnik, Wiktor Obuchowski, Characterisation of the extruded cereal snacks containing potato juice , Bulletin of Plant Breeding and Acclimatization Institute: No. 266 (2012): Regular issue
- Grażyna Lewandowicz, Przemysław Kowalczewski, Wojciech Białas, Anna Olejnik, Joanna Rychlik, Separation of the fractions of potato juice of different molecular weight and characterization of their biological activities , Bulletin of Plant Breeding and Acclimatization Institute: No. 266 (2012): Regular issue
Similar Articles
- Zbigniew Czerko, Magdalena Grudzińska, Influence of weather and storage conditions on sprouting of potato tubers , Bulletin of Plant Breeding and Acclimatization Institute: No. 271 (2014): Regular issue
- Joanna Le Thanh-Blicharz, Jacek Anioła, Aleksander Walkowski, Grażyna Lewandowicz, Digestibility of diets containing RS modified starches assessment in rats , Bulletin of Plant Breeding and Acclimatization Institute: No. 266 (2012): Regular issue
- Jerzy Osowski, Janusz Urbanowicz, The influence of microstarters B and K on the volume and quality of potato tubers , Bulletin of Plant Breeding and Acclimatization Institute: No. 292 (2020): Special issue
- Anna Płaza, The after-effect of catch crop and straw on productive-economic effects of winter triticale cultivation , Bulletin of Plant Breeding and Acclimatization Institute: No. 247 (2008): Regular issue
- Barbara Lutomirska, Joanna Jankowska, Influence of meteorological factors on occurrence and severity of black scurf on potato tubers , Bulletin of Plant Breeding and Acclimatization Institute: No. 273 (2014): Regular issue
- Barbara Łotocka, Marcin Kozak, Krystyna Rykaczewska, Morphology and anatomy of the root system of new potato cultivars. Part II. Root anatomy , Bulletin of Plant Breeding and Acclimatization Institute: No. 279 (2016): Regular issue
- Marian Flis, Procedure for estimation of damage inflicted by wild animals in agricultural crop stands , Bulletin of Plant Breeding and Acclimatization Institute: No. 248 (2008): Regular issue
- Janusz Urbanowicz, The occurrence of weeds and methods of their control in potatoes in Poland in the years 2000–2011 , Bulletin of Plant Breeding and Acclimatization Institute: No. 265 (2012): Regular issue
- Milena Pietraszko, Development of potatoes fungal diseases and the amount of tuber yield depending on the scope of protection , Bulletin of Plant Breeding and Acclimatization Institute: No. 292 (2020): Special issue
- Teresa Pastuszewska, Katarzyna Franke, Mirosław Nowakowski, Effect of white mustard on density of potato cyst nematode (Globodera rostochiensis) population in soil , Bulletin of Plant Breeding and Acclimatization Institute: No. 269 (2013): Regular issue
<< < 16 17 18 19 20 21 22 23 24 > >>
You may also start an advanced similarity search for this article.
